Thursday, August 4, 2016

800 Viruses That Threaten the World [Video]

A powerful documentary chronicles the mysterious viruses, such as Ebola and Zika, that jump from animals to people—any one of which could one day cause the next great pandemic

By Christine Gorman on August 2, 2016


Researcher Jon Epstein and a colleague feed a bat mango juice before it is released. Credit: Courtesy of Tangled Bank Studios, LLC

Those of us who live in big cities or sprawling suburbs often forget how much our health and well-being are tied to the plants, animals and other organisms with whom we share this planet. Sometimes the relationship is mutually beneficial—as when the friendly bacteria in our gut crowd out the dangerous ones. Other times, too much closeness triggers new diseases and devastating epidemics—as occurs when a burgeoning human population consumes entire forests and jungles to survive.

The negative consequences take center stage in a powerful new PBS documentary, "Spillover—Zika, Ebola & Beyond," set to premier this Wednesday night. In just a couple of hours, this incredibly engaging film chronicles the growing number of viruses that make the jump, or spill over, from animals to people. As you might expect, the filmmakers spend most of their time on the two biggest recent spillover events: the 2014 Ebola outbreak in West Africa and the current Zika epidemic in the Americas.

Both cases stunned international health experts with their ferocity and rapid spread. Indeed, the whole globe may owe Amayo Adadevoh an enormous debt of gratitude. As chief doctor at the First Consultant hospital in Lagos, she quarantined a patient who had traveled to Nigeria in the summer of 2014 with what the clinician suspected was Ebola. Then she resisted intense pressure to release him. Her courage and professionalism—and those of several other doctors and nurses at the hospital—quite likely stopped the virus from spreading throughout the populous country and beyond to the rest of world. She paid for her constancy with her life, having herself succumbed to Ebola herself on August 19, 2014.

PBS has given us permission to share a clip from “Spillover.” I chose one about Nipah, yet another viral threat that emerged in the late 1990s in Southeast Asia, because it is not as well known as either Ebola or Zika. For as long as anyone can remember, people in Bangladesh have enjoyed raw sap drinks collected from palm trees during the winter. It turns out that fruit bats like to avail themselves of the collection pots for an illicit sip of sap at night. And as the clip demonstrates, Nipah likely jumped from bats to people over the course of time because both of them shared a fondness for sweet palm juice.



Ebola, Zika and Nipah are just three of at least 800 spillover viruses that have been identified to date. By some estimates the number of times that viruses cross species barriers to cause diseases in people has quadrupled in the past half century. No one knows how many more there might be. But there can be no doubt, as Tom Frieden of the Centers for Disease Control and Protection puts it in the film, “[These viruses] all show us one essential fact. Threats are emerging. We will have another health threat. I can’t tell you what it will be or when it will be here, but we know with 100% certainty that it will occur.”

Finally, the last words of “Spillover” are some of the most philosophical that I have ever heard coming from a public health official. “Unless we accept that our fate is linked across people and across animals, across the world,” says name Emily Gurley of the International Center of Diarrheal Disease Research in Dhaka. “Then we’re never going to do what’s needed to get ahead of these kinds of public health threats.”

blogs.scientificamerican.com

1 comment:

  1. On Aug 6, 2016, at 8:30 AM, donpatent wrote:

    Dear Gene;

    You may find these interesting:

    http://virusvisions.blogspot.ca/
    http://donpatent.blogspot.ca/

    Don


    Re: My blogs
    Inbox
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    eugeneseymourmd
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    eugeneseymourmd@mac.com
    11:30 AM (16 minutes ago)

    to me
    I did!

    Please keep sending these links as you aggregate the content

    I saw the documentary

    Very well done

    Jon Epstein is extensively mentioned in David Quammen’s book entitled “Spillover”

    Quite a fascinating read

    Every biotech CEO that I’ve spoken to who works in the vaccine or anti-viral space is hanging back with regard to Zika until the funding is straightened out.

    Things are looking good for the vaccines now being tested but the need is still there for an effective anti-viral. A friend who tested the first anti-viral (by a multi-billion company) told me that it failed miserably. The tox and clinical trials will be a nightmare because you have to treat a large number of pregnant women to achieve any degree of statistical relevance with regards to the microcephaly issue.

    Unless the US comes up with some serious money, I wonder if anyone will tackle the anti-viral development and clinical trial task

    Gene

    Eugene Seymour MD MPH
    Chief Executive Officer
    NanoViricides, Inc
    eugene@nanoviricides.com
    www.nanoviricides.com
    310-486-5677
    "NNVC" on the New York Stock Exchange

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